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Oculoplastics

Merkel Cell Carcinoma: An Uncommon Tumor Without a Definitive Treatment Protocol

Mark R. Levine, MD · Amarpreet Singh, MD · Marc R. Criden, MD

Click on each slide to view a larger image.

Slide 1 Slide 1. Merkel cell carcinoma presenting as a deeply violaceous lower lid nodule.
Slide 2 Slide 2. Lesion of the left upper lobe showing the characteristic telangiectases seen in MCC.
Slide 3 Slide 3. Patient who presented with an ulcerated lesion with rolled edges in MCC. The patient was initially diagnosed with basal cell carcinoma.
Slide 4 Slide 4. Patient who presented with an ulcerated lesion with rolled edges in MCC. The patient was initially diagnosed with basal cell carcinoma.
Slide 5 Slide 5. Patient who presented with MCC and was initially diagnosed with recurrent chronic chalazion.
Slide 6 Slide 6. Histopathology showing trabecular MCC with a growth pattern of polygonal and round cells with abundant cytoplasm.
Slide 7 Slide 7. Histopathology of intermediate MCC with less abundant cytoplasm than trabecular MCC.
Slide 8 Slide 8. EM transmission of MCC. The cytoplasmic neurosecretory granules (indicated by arrows) are 80 nm to 120 nm.

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